SNPStats: a web tool for the analysis of association studies

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Abstract
Summary: A web-based application has been designed from a genetic epidemiology point of view to analyze association studies. Main capabilities include descriptive analysis, test for Hardy–Weinberg equilibrium and linkage disequilibrium. Analysis of association is based on linear or logistic regression according to the response variable (quantitative or binary disease status, respectively). Analysis of single SNPs: multiple inheritance models (co-dominant, dominant, recessive, over-dominant and log-additive), and analysis of interactions (gene–gene or gene–environment). Analysis of multiple SNPs: haplotype frequency estimation, analysis of association of haplotypes with the response, including analysis of interactions. Availability: . Source code for local installation is available under GNU license. Contact:v.moreno@iconcologia.net Supplementary Information: Figures with a sample run are available on Bioinformatics online. A detailed online tutorial is available within the application.