The role of histamine in wound healing I. The effect of high doses of histamine on collagen and glycosoaminoglycan content in wounds
- 1 July 1977
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 7 (2) , 219-224
- https://doi.org/10.1007/bf01969976
Abstract
The effect of high doses of histamine (Hi) on collagen and glycosoaminoglycan (GAG) content in skin wounds of rats was studied on days 1, 3, 5, 10 and 14 after wounding. Injection of high doses of Hi into the wounded area inhibited collagen production, collagen polymerization and GAG synthesis; levels of chondroitin sulphates (chondroitin-4,6-sulphate and dermatan sulphate) and hyaluronic acid were decreasedThis publication has 22 references indexed in Scilit:
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