A response of arteriolar smooth muscle cells to injury.

  • 1 August 1969
    • journal article
    • Vol. 50  (4) , 356-60
Abstract
Arterioles in the pancreas and submandibular gland of the rat were examined after small pieces of the glands had been incubated in non-oxygenated Tyrode solution at 20° for 1 hr. It was found that processes from smooth muscle cells invaded the cytoplasm of adjacent cells to form double-membraned inclusions which remained connected to the parent cell by a narrow neck of cytoplasm. These inclusions were electron-lucent and appeared to contain watery or swollen cytoplasm. It is suggested that their formation may be a common and characteristic response of smooth muscle cells to injury.