Facile Conversion of Aldehydes into 1-Substituted 2-Chloro-3,3-difluoro-2-propen-1-ols with 1,1-Dibromo-1-chloro-2,2,2-trifluoroethane/Magnesium Reagent
- 1 September 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 61 (9) , 3321-3322
- https://doi.org/10.1246/bcsj.61.3321
Abstract
Aldehydes RCHO are converted in excellent yields into chlorodifluoroallyl alcohols RCH(OH)CCl=CF2 upon treatment with CClBr2CF3 and magnesium in tetrahydrofuran at 0 °C.Keywords
This publication has 7 references indexed in Scilit:
- Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and ZincBulletin of the Chemical Society of Japan, 1987
- Practical, Stereocontrolled Synthesis of Polyfluorinated Artificial PyrethroidsBulletin of the Chemical Society of Japan, 1987
- Reduction d'alcools allyliques fluores par le borohydrure de sodiumTetrahedron Letters, 1987
- Practical ways from aldehydes to 2-chloro-1,1,1-trifluoro-2-alkenes and 2-chloro-1,1-difluoro-1-alken-3-olsTetrahedron Letters, 1986
- Highly regio- and stereocontrolled halogenation of 1,1-difluoro-2-halo-1-alken-3-ols as applied to polyfluorinated pyrethroid synthesisTetrahedron Letters, 1986
- Fluoride ion catalyzed aldehyde addition of labile .alpha.- or .beta.-halo carbanion species generated from the corresponding .alpha.- or .beta.-halo organosilanesJournal of the American Chemical Society, 1985
- Synthese de difluoroolefines transTetrahedron Letters, 1983