Trends in Clinical and Basic Amyloid Research

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Abstract
After 100 years of slow progress, research on amyloid disease has come of age along with the many technical advances of the past decade. Since the detailed review in the Journal,1 the concept of the apparent clinical rarity of amyloidosis gave way to a concept of its virtual universality, especially as an accompaniment of aging.2 The careful clinical study by Ozdemir, Wright and Calkins in this issue raises appropriately the need for a more scientific approach to our clinical as well as basic thinking concerning its incidence. The idea that widespread amyloid may not be common in rheumatoid arthritis . . .

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