Benign Obstetric History in Women with Sickle-cell Anaemia Associated with -Thalassaemia
- 2 December 1972
- Vol. 4 (5839) , 524-526
- https://doi.org/10.1136/bmj.4.5839.524
Abstract
Two Ghanaian women with sickle-cell anaemia and α-thalassaemia were found to have an unusually benign obstetric history. In addition to two factors present which are known to moderate the clinical course of sickle-cell anaemia, good socioeconomic status and a relatively high Hb F level, it is suggested that α-thalassaemia may act among other things by lowering the haemoglobin concentration in the red cells and thereby lowering their tendency to sickle in vivo.Keywords
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