Brucella in Tissues Removed at Surgery

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Abstract
Brucella organisms may be isolated from surgical specimens when there is no obvious history or clinical course to suggest brucellosis. The agglutination reactions on serum are usually positive but may be negative in certain cases of chronic brucellosis. The gross and microscopic appearances of a lesion may be nonspecific or they may be strikingly similar to tuberculosis. Histologic examination alone is misleading in the diagnosis of chronic lesions due to Brucella. Brucella may be unrecognized as the cause of bursitis unless the organism is isolated by bacteriologic methods. Surgical removal of a localized lesion may be required as a supplement to chemotherapy, even though the diagnosis of brucellosis is already established.

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