The Colorimetric Microestimation of Human Blood Cholinesterases and Its Application to Poisoning by Organic Phosphate Insecticides12

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Abstract
A colorimetric method for the detn. of human plasma and red cell cholinesterases on finger puncture blood was developed. It is rapid and precise and can be used with as little as 1 [mu]l. of plasma. The conditions for the satisfactory performance of the method are outlined in detail, and values are presented for expected normal variations in a single subject and in a group of human males. It is suggested that this method may be of value in determining dangerous over-exposure to organic phosphate insecticides and Pharmaceuticals, and in studies of the action of these materials on laboratory animals.