Isolation and identification by FAB mass spectrometry and NMR spectroscopy of a demethylated metabolite of FK506 from erythromycin-induced rabbit liver microsomes
- 31 July 1993
- journal article
- Published by Elsevier in Pharmaceutica Acta Helvetiae
- Vol. 68 (1) , 35-41
- https://doi.org/10.1016/0031-6865(93)90006-r
Abstract
No abstract availableKeywords
This publication has 4 references indexed in Scilit:
- In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: Identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolismArchives of Biochemistry and Biophysics, 1992
- Isolation of an isomer of FK-506 from fermentation of Streptomyces tsukubaensis and its chemical synthesis from FK-506Tetrahedron, 1992
- Structure of FK506, a novel immunosuppressant isolated from StreptomycesJournal of the American Chemical Society, 1987
- ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVERThe Journal of cell biology, 1974