Evaluation of Corticosteroid and Exchange-Transfusion Treatment of Acute Yellow-Phosphorus Intoxication
- 21 January 1971
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 284 (3) , 125-128
- https://doi.org/10.1056/nejm197101212840303
Abstract
To evaluate steroid therapy in patients acutely intoxicated with yellow phosphorus, 49 patients were sequentially assigned to one of three groups. Group A did not receive steroids at any time, Group B received steroids from the time of admission, and steroids were used in Group C only when liver coma developed. Two out of four patients in coma recovered in Group A, none out of five in Group B, and four out of seven in Group C. Thus, steroids did not appear to prevent onset of coma in this type of liver injury and did not increase survival after development of coma.Keywords
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