The association of a lymphoreticular malignancy with an 11q deletion: A coincidence or a cancer susceptibility?
- 1 June 1983
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 63 (4) , 323-326
- https://doi.org/10.1007/bf00274755
Abstract
A balanced paternal chromosome insertion, ins(11) p14q14q21, resulted in a female with an unbalanced karyotype, del(11)(q14q21). This imbalance presumably arose from a meiotic crossover between the breakpoint of the insertion and the breakpoints of the deletion. This child developed a malignant lymphoma of the thymus in the first year of life. The association of a lymphoma with an 11q deletion may not be a coincidence in view of the frequent involvement of 11q in cytogenetic alterations of lymphomas.This publication has 22 references indexed in Scilit:
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