Radioprotective Effects of Prostaglandins for Chromosomal Aberrations and Cell Killing in V79 Chinese Hamster Cells Grown as Spheroidsin Vitroand for Mouse Spermatogonial Stem Cells and Bone Marrow Cellsin Vivo
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 67 (1) , 47-55
- https://doi.org/10.1080/09553009514550061
Abstract
The radioprotective effects of prostaglandins (PGE2, PGE1 and its analogue misoprostol (MP) were investigated in cultures of V79 Chinese hamster (CHO) cells grown as spheroids and as monolayers, CHO cells grown as monolayers, and in bone marrow polychromatic erythrocytes and spermatogonial stem cells in mouse. The X-ray doses were 0·75 Gy (hamster cells) and 5, 8 and 10 Gy (mouse experiments).Keywords
This publication has 34 references indexed in Scilit:
- Topical or Systemic 16,16 Dm Prostaglandin E2or WR-2721 (WR-1065) Protects Mice from Alopecia after Fractionated IrradiationInternational Journal of Radiation Biology, 1992
- The relation between induced reciprocal translocations and cell killing of mouse spermatogonial stem cells after combined treatments with hydroxyurea and X-raysMutation Research Letters, 1990
- A search for radiosensitive mouse mutants by use of the micronucleus techniqueMutation Research Letters, 1987
- Prostaglandins, Prostacyclin, and ThromboxanesAnnual Review of Pharmacology and Toxicology, 1981
- Effects of intercellular contact on repair of radiation damageExperimental Cell Research, 1972
- A new concept of spermatogonial stem-cell renewal in the mouse and its relationship to genetic effectsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1971