Azidothymidine(AZT)‐induced siderosis

1 July 1993

journal article
research article
Published by Wiley in American Journal of Hematology

Vol. 43 (3) , 230-233
https://doi.org/10.1002/ajh.2830430314

Abstract

Azidothymidine(AZT) interferes with heme synthesis. This should upregulate the synthesis of transferrin receptors and increase the amount of iron taken up by the cell. We found a 50% increase in the iron content of liver and a 20% increase in the iron content of macrophages in AZT-treated mice.

Keywords

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