Comparative studies of plaque variantes derived from a Florida strain of Venezuelan equine encephlomyelitis virus.

  • 1 November 1972
    • journal article
    • Vol. 6  (5) , 779-84
Abstract
Small- and large-plaque variants of a Florida strain (Fe 3-7c) of Venezuelan equine encephalomyelitis virus were studied in vivo and in vitro. The small-plaque variant was less virulent in mice, hamsters, and guinea pigs than the large-plaque variant. The variants could be distinguished by calcium phosphate chromatography. The implications of plaque variants within a mixed virus population are discussed.