Azasulfonamidopeptides as peptide bond hydrolysis transition state analogues. Part 1. Synthetic approaches
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 1595-1600
- https://doi.org/10.1039/p19940001595
Abstract
The title compounds, a novel class of peptide analogues in which an α-amino acid residue is replaced by a hydrazine-1, 2-diyl sulfonyl group -NHNRSO2-, are of potential interest as proteinase inhibitors. Synthetic approaches to such compounds and the X-ray molecular structures of two examples (16 and 28) are reported.Keywords
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