Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 12 (3) , 1641-1655
- https://doi.org/10.1093/nar/12.3.1641
Abstract
Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.Keywords
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