Pulmonary blood volume in hemorrhagic shock in the dog and primate

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Abstract
Pulmonary blood volume, vascular resistance, and diffusing capacity for CO were compared in the baboon and the dog during experimental hemorrhagic shock. Control pulmonary blood volume represented a larger proportion (6.8%) of total blood volume in the monkey than in the dog (5.4%) associated with greater pulmonary vascular resistance. Proportional decreases in volume occurred in both species during hemorrhagic and postinfusion shock, accompanied by increased resistance. Pulmonary diffusing capacity for CO decreased during the bleeding and postinfusion periods, paralleling the decrease in pulmonary arterial and left atrial pressures. No evidence was found for significant pooling of blood in the pulmonary vascular system. The baboon showed a significant decrease in 131I measured blood volume during the later portions of the postinfusion phase. Total systemic resistance failed to increase in the dog experiments.

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