Changes in Response to Inhalation of CO2 Before and After 24 Hours of Hyperventilation in Man
- 1 October 1948
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 1 (4) , 333-338
- https://doi.org/10.1152/jappl.1948.1.4.333
Abstract
Respiratory ventilation responses to CO2-O2 mixtures before and after 14 hrs. of hyper-ventilation in a body respirator were detd. on 3 young, healthy, male medical students. Two of the subjects showed an increase in ventilation response to the 3 concns. of CO2 (2.5%, 5%, and 7.5% CO2 in oxygen)after the hyperventilation, while the 3d exhibited an increase in response to the highest concn. of CO2 but not to the 2 lower concns. Stimulus response curves, constructed by plotting alveolar pCO2 against alveolar ventilation ratio, showed an increase in slope in 2 of the 3 subjects when responses after 24 hrs. of hyperventilation were compared with responses before hyperventilation.Keywords
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