Localization of talin in skeletal and cardiac muscles
- 5 May 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 200 (1) , 32-36
- https://doi.org/10.1016/0014-5793(86)80505-1
Abstract
Antibodies to talin and vinculin were used for localization of these proteins in skeletal and cardiac muscles by the indirect immunofluorescence method. We have found that talin is localized in intercalated discs of cardiac muscle and in costameres of skeletal and cardiac muscles. It is suggested that in striated muscles talin and vinculin play an important role in interactions between actin filaments and membranes.Keywords
This publication has 12 references indexed in Scilit:
- An interaction between vinculin and talinNature, 1984
- Vinculin is a component of an extensive network of myofibril-sarcolemma attachment regions in cardiac muscle fibers.The Journal of cell biology, 1983
- Vinculin localization in cardiac muscleFEBS Letters, 1983
- A new protein of adhesion plaques and ruffling membranes.The Journal of cell biology, 1983
- A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements ("costameres") mark sites of attachment between myofibrils and sarcolemma.Proceedings of the National Academy of Sciences, 1983
- Ultrastructure of chicken cardiac muscle as studied by double immunolabeling in electron microscopy.Proceedings of the National Academy of Sciences, 1981
- Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells.The Journal of cell biology, 1981
- Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.Proceedings of the National Academy of Sciences, 1980
- Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectinCell, 1980
- A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cellsCell, 1979