XXXVIII Sensorineural Deafness and Otosclerosis

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Abstract
The morphological changes changes present in the serially sectioned temporal bones from 2 patients with clinical otosclerosis and total loss of cochlear function are discussed. Both patients represent unusual examples of a diffuse otosclerotic process involving vast areas of the otic capsule. The extensive otosclerotic bone transformations caused obvious distortions of the contours of the cochlea, radial and axial distortion of the modio-lus and numerous tiny spontaneous fractures of the modiolar septa. Wherever the otosclerotic process involves the adjacent spiral ligament obvious pathological changes have occurred in the stratum fibrosum of the ligament and in the stria vascularis. All 4 ears also have extensive degenerative changes of the organ of Corti and the peripheral cochlear neuron. It may be assumed that the otosclerotic process, because of its location, extent and characteristics, was responsible for the ultimately total loss of cochlear function in these 2 patients.

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