GENETICS OF OSTEOPOROSIS
- 1 November 1994
- journal article
- review article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 33 (11) , 1007-1011
- https://doi.org/10.1093/rheumatology/33.11.1007
Abstract
Identification of the major contribution of genetic factors in determination of peak bone mass at skeletal maturity and possibly on subsequent age-related bone loss has led to efforts to identify possible mechanisms. Recent evidence suggests one mechanism relates to genetic effects on bone turnover mediated via the vitamin D system. This field of research has potential for reducing osteoporotic fracture risk by allowing interventions at different stages in life to reduce this increasing problem of ageing societies.Keywords
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