Hairpin Formation and Elongation of Biomolecules
- 5 March 2001
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 86 (10) , 2178-2181
- https://doi.org/10.1103/physrevlett.86.2178
Abstract
We introduce a model of thermalized conformations in space of RNA—or single stranded DNA—molecules, which includes the possibility of hairpin formation. This model contains the usual secondary structure information, but extends it to the study of one element of the ternary structure, namely the end-to-end distance. The computed force-elongation characteristics are in good agreement with some recent measurements on single stranded DNA molecules.Keywords
This publication has 19 references indexed in Scilit:
- Sequence-dependent mechanics of single DNA molecules.Nature Structural & Molecular Biology, 1999
- DNA strand separation studied by single molecule force measurementsPhysical Review E, 1998
- Behavior of Supercoiled DNABiophysical Journal, 1998
- The Elasticity of a Single Supercoiled DNA MoleculeScience, 1996
- Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA MoleculesScience, 1996
- DNA: An Extensible MoleculeScience, 1996
- Entropic Elasticity of λ-Phage DNAScience, 1994
- DNA Extension under the Action of an External ForceMacromolecules, 1994
- RNA secondary structure: a comparison of real and random sequencesJournal de Physique I, 1993
- Direct Mechanical Measurements of the Elasticity of Single DNA Molecules by Using Magnetic BeadsScience, 1992