Acquired QT interval prolongation and HERG: implications for drug discovery and development
- 20 August 2004
- journal article
- review article
- Published by Elsevier in European Journal of Pharmacology
- Vol. 500 (1-3) , 129-142
- https://doi.org/10.1016/j.ejphar.2004.07.019
Abstract
No abstract availableKeywords
This publication has 96 references indexed in Scilit:
- Trends in ion channel drug discovery: advances in screening technologiesTrends in Biotechnology, 2003
- The open pore conformation of potassium channelsNature, 2002
- The pre-clinical assessment of QT interval prolongation: a comparison of in vitro and in vivo methodsHuman & Experimental Toxicology, 1998
- The Structure of the Potassium Channel: Molecular Basis of K + Conduction and SelectivityScience, 1998
- Epidemiology and Relative Toxicity of Antidepressant Drugs in OverdoseDrug Safety, 1997
- The Spectrum of Symptoms and QT Intervals in Carriers of the Gene for the Long-QT SyndromeNew England Journal of Medicine, 1992
- Determination of the subunit stoichiometry of a voltage-activated potassium channelNature, 1991
- Cloning of Genomic and Complementary DNA from Shaker , a Putative Potassium Channel Gene from DrosophilaScience, 1987
- The long QT syndrome: a prospective international study.Circulation, 1985
- Heritable Q-T Prolongation Without DeafnessCirculation, 1970