Stereoselective Syntheses of ALKYL- and ALKYL-2-THIO-α-Sialosides

Abstract
Alkyl and thioalkyl α-glycosides of N-acetylneuraminic acid have been prepared in near quantitative yield and with complete stereoselectivity, under the Williamson reaction conditions using RONa or RSNa, respectively, in ROH or RSH as solvent.