Synthesis of (2R,3S)‐1,2,3‐Butanetriol Derivatives From (R)‐2,3‐O‐Isopropylideneglyceraldehyde and of the (2S,3R)‐Enantiomers From D‐Glucose. Application to the Synthesis of Enantiomerically Pure Muscarine

Abstract
Both enantiomers of the O‐protected epoxy alcohol derivative 1b have been prepared from (R)‐2,3‐O‐isopropylideneglyceraldehyde and D‐glucose, respectively, and utilized in a practical synthesis of L‐ and D‐muscarine iodide and chloride.

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