Studies in Carbohydrate Metabolism

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Abstract
Following the ingestion of dihydroxyacetone by normal individuals and diabetic patients, an increased O consumption was observed and a rise in the respiratory quotient more marked than that following glucose ingestion. Dihydroxyacetone, then, may be either directly oxidized or rapidly changed into a substance which can be. These observations are in accord with the hypothesis that insulin facilitates the transformation of glucose into dihydroxyacetone, which is then directly oxidized.

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