Breast Cancer and the Pedigree Relationship of Fostered a Stock Mice

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Abstract
The breast cancer ratio in breeding [female][female] of the "A" strain of mice was reduced from 83.6% to 7.9% by fostering the young as soon as born to low cancer-stock mothers. Fostered [female][female] which were non-cancerous had progeny with an incidence of 6.1%; fostered [female][female] which developed breast cancer had progeny with a ratio of 58.5%. 1093 control mice and 734 fostered [female][male] and their progeny were observed. "A" stock young which were permitted to nurse their high-tumor mothers for 24 hrs. or longer before being fostered showed a high mammary-cancer incidence (86.7%) as did young born to non-cancerous fostered [female][female] which were given to high-cancer [female][female] (88.9%). When breast cancer developed in the progeny of tested non-breast cancerous fostered [female][female] it was not transmitted (5.3%).

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