Organophosphorus Insecticides in Colorado

Publisher Website
Google Scholar
Abstract
A study was made from 1955 to 1961 on the occurrence of exposure to organophosphorus insecticides in the Colorado area. A reduction in blood cholinesterase activity was taken as evidence for significant absorption of these compounds in persons working with the organophosphorus insecticides. Of 419 blood samples submitted, 43% showed evidence of some absorption, while 19% showed evidence of marked absorption of the organophosphorus insecticides. In the latter group, all workers had symptoms of toxicity. A total of 70 persons required admission either to the hospital or to the Emergency Room for treatment. In routine blood sampling of workers in airplane spraying groups, over 60% showed reduced blood cholinesterase activity, which emphasizes a need for improving working techniques. Studies were presented to show how effective protective procedures could reduce significantly absorption of the organophosphorus insecticides in persons working with these agents. A community approach designed to reduce organophosphorus insecticide toxicity in workers and to provide improved therapy was outlined.