Metachronous colorectal malignancies

Abstract
Sixty-two patients with metachronous colorectal malignancies who underwent surgery were reviewed. Fifty percent of the patients developed a 2nd carcinoma within 5.5 yr from the time of resection of their 1st tumor and the time interval for the entire group ranged from 1-23 yr. Adenomas of the colon or rectum occurred in 25 of the 62 patients (40%). A negative correlation was noted between the age of the patients at the time of their 1st operation and the time interval in years from the 1st to 2nd resections. The 5-yr cumulative probability of survival of the 62 patients after resection of the metachronous lesions was 59%. Seven of the 62 patients (11%) developed a 3rd metachronous lesion. Adequate treatment for metachronous colorectal malignancies should imply surgery with a curative intent and after resection of a 1st colorectal carcinoma, lifelong, periodic, total colonic evaluation is essential.

This publication has 16 references indexed in Scilit: