Macromolecular Properties of Hexadimethrine Bromide, an Antiheparin Agent

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Abstract
Summary 1. Previously reported light scattering molecular weights of hexadimethrine bromide are in error due to the presence of fluorescent material. The true molecular weights are much lower and may in fact be nearly identical for all commercial samples. 2. Fractionation by gel filtration followed by pharmacological and toxicological studies indicate that a polymer of 4 monomer units would be the preferred one for clinical use.