In Situ Hybridization of Papillomavirus DNA in Head and Neck Squamous Cell Carcinomas
- 1 August 1987
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 113 (8) , 819-821
- https://doi.org/10.1001/archotol.1987.01860080025008
Abstract
• Cytospin preparations of fine-needle aspirates obtained from five squamous cell carcinomas of the head and neck (four metastatic in lymph nodes and one primary) were tested for human papillomavirus (HPV) genotypes 6, 11, 16, and 18 by in situ hybridization using biotinylated DNA probes. All five carcinomas showed hybridization with HPV-11, four strongly reactive, and one also weakly hybridized with HPV-16. Genotypes 6 and 18 showed no evidence of hybridization. (Arch Otolaryngol Head Neck Surg 1987;113:819-821)This publication has 6 references indexed in Scilit:
- PRESENCE OF HUMAN PAPILLOMAVIRUS TYPE-16 RELATED SEQUENCES IN VERRUCOUS CARCINOMA OF THE LARYNX1986
- Molecular cloning and characterization of the dna of a new human papillomavirus (hpv 30) from a laryngeal carcinomaInternational Journal of Cancer, 1986
- Detection of viral DNA and RNA by in situ hybridization.Journal of Histochemistry & Cytochemistry, 1986
- Identification of genital tract papillomaviruses HPV‐6 and HPV‐16 in warts of the oral cavityJournal of Medical Virology, 1985
- HUMAN GENITAL CANCER: SYNERGISM BETWEEN TWO VIRUS INFECTIONS OR SYNERGISM BETWEEN A VIRUS INFECTION AND INITIATING EVENTS?The Lancet, 1982
- Viral etiology of juvenile- and adult-onset squamous papilloma of the larynx.Proceedings of the National Academy of Sciences, 1982