The Role of Leptin in Human Obesity and Disease: A Review of Current Evidence
- 20 April 1999
- journal article
- review article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 130 (8) , 671-680
- https://doi.org/10.7326/0003-4819-130-8-199904200-00014
Abstract
Since leptin was discovered 4 years ago, understanding of the mechanisms underlying neuroendocrine function, body weight, and energy homeostasis has greatly broadened. Elucidation of these mechanis... Purpose: To review recent advances in the pathophysiology and potential clinical applications of leptin, an adipose tissue-derived hormone. Data Sources: A MEDLINE search of the literature on lepti...Keywords
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