Tolerance and Contact Sensitivity to DNFB in Mice. II. Specific in Vitro Stimulation with a Hapten, 2,4-Dinitrobenzene Sulfonic Acid (DNB·SO3Na)

Abstract
Summary: A hapten, 2,4-dinitrobenzene sulfonic acidsodium salt (DNB·SO3Na), a tolerogen, was shown to stimulate (in vitro) specifically lymph node or spleen cells from mice contact-sensitized to DNFB. This stimulation could be carried out in the absence of added serum. Cells from normal and from tolerant mice were not stimulated by DNB·SO3Na.

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