Body Iron Stores and the Risk of Coronary Heart Disease

Abstract
Sempos and coworkers report data from the National Health and Nutrition Examination Survey (NHANES I) Epidemiologic Follow-up Study (NHEFS) and conclude that “higher transferrin-saturation levels were not associated with an increased risk of coronary heart disease or myocardial infarction” (April 21 issue).1 Since their finding appears to conflict with ours,2 we report the results of the extended follow-up of the Kuopio Ischaemic Heart Disease Risk Factor Study.