Measles Vaccine Field Trials in Alaska
- 3 August 1964
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 189 (5) , 339-342
- https://doi.org/10.1001/jama.1964.03070050005001
Abstract
Two regimens of measles vaccination were tested in Alaskan Eskimo villages in March, 1963. Clinical reactions to vaccines were no more severe than those observed in other populations. From 7 to 11 days following administration of live attenuated vaccine plus γ-globulin, 18% of vaccinees had a temperature of 103 F (39.4 C) and 24% developed a rash. One dose of killed vaccine followed in six weeks by live attenuated vaccine produced a temperature of 102 F (38.9 C) in only two instances and measles-like rash was not observed. Height of antibody response following live attenuated vaccine and γ-globulin was related significantly to age and maximum temperature. Rash occurred more frequently in the very young.Keywords
This publication has 0 references indexed in Scilit: