Does Infection Play a Role in Breast Capsular Contracture?

Publisher Website
Google Scholar
Abstract
The role of subclinical infection with Staphylococcus epidermidis as a cause of capsular contracture was evaluated in 16 rabbits using miniature silicone implants. All the implants on the side contaminated with varying concentrations of S. epidermidis developed breast capsular contractures. Using Baker''s classification, they were graded III or IV; the controls were all considered to be either grade I or II. Grossly, the capsules on the contaminated side were firm, fibrous and 2-3 times thicker than the controls; this was confirmed histologically using micrometry. Implants contaminated with 107 bacteria uniformly extruded. Thus, subclinical infection with S. epidermidis may be a cause of capsular contracture around breast implants.

This publication has 0 references indexed in Scilit: