CIRCULATING IMMUNOGLOBULIN-SECRETING CELLS IN PATIENTS WITH PLASMA-CELL DYSCRASIA
- 1 January 1980
- journal article
- research article
- Vol. 55 (4) , 590-594
Abstract
Immunoglobulin-secreting cells (ISC) in peripheral blood mononuclear cells (PBM) isolated from patients with plasma cell dyscrasia of various stages were studied using reverse hemolytic plaque assay. Normal healthy individuals contained 35 .+-. 16 ISC/105 PBM. Aleukemic or subleukemic patients with overt myeloma contained 825 .+-. 713 ISC, whereas leukemic patients contained 12,675 .+-. 2520 ISC. Patients of premyelomatous stage contained ISC/105 PBM of normal range. The relationship between ISC and clinical or laboratory data was discussed.This publication has 2 references indexed in Scilit:
- Multiple Myeloma and Benign Monoclonal Gammopathy: Differentiation by Immunofluorescence of LymphocytesAnnals of Internal Medicine, 1973
- Circulating Plasma Cells in Multiple MyelomaAnnals of Internal Medicine, 1962