Cochlear Neural Degeneration Without Hair Cell Loss in Two Patients with Aminoglycoside Ototoxicity
- 1 September 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 156 (3) , 449-455
- https://doi.org/10.1093/infdis/156.3.449
Abstract
The temporal bones of two young adults who developed auditory toxicity during or shortly after a course of aminoglycoside therapy were examined by using light microscopy. Although the organs of Corti were essentially normal, the total number of cochlear ganglion cells was about one-third lower than the number observed in comparable subjects with normal hearing.Keywords
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