Hemorrhage Without Hypotension

Abstract
Before and at frequent intervals for one hour following 14 cc/kg hemorrhage, the flow was measured in the following vessels or areas of the dog: coronary, brachiocephalic, left subclavian, descending aorta, abdominal aortic inflow, splanchnic area (excluding renal), somatic (hind limbs), and ascending aorta. Eight hundred separate flow measurements were performed. A marked discrepancy was noted between alterations in arterial blood pressure and change in cardiac output: cardiac output was reduced 40% when blood pressure was reduced only 15%. There was preferential maintenance and often absolute increase in coronary flow (59 of 115 measurements). Early marked reduction in renal blood flow was followed by return to levels equalling or exceeding control values in 40 of 100 measurements. Shift of blood flow away from the gastro- intestinal area was noted but was felt to be of borderline significance. Marked shift of flow away from the hind limb somatic area was noted.