Screening for Proteinuria in US Adults

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Abstract
Chronic kidney disease is a growing public health problem. More than 10 million US adults have some kidney damage (serum creatinine levels ≥1.5 mg/dL [132.6 µmol/L]), and the number of persons with end-stage renal disease (ESRD) exceeds 300 000. Persons with ESRD, who have a poor quality of life and accrue high health care costs, are projected to exceed 600 000 in 2010.1-4 Early identification and treatment of patients who are more likely to progress to ESRD to decrease mortality, morbidity, and costs associated with chronic kidney disease has been debated. Controversy exists because many patients do not progress to ESRD, however, the majority of those who do progress go undetected until it is too late to intervene.5

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