Abstract
The most stable conformation of the hexamethyl ether of scyllo-inositol (all-trans-cyclohexan-1, 2, 3, 4, 5, 6-hexol) is calculated to be the one with six equatorial methoxy groups with in each case the oxygen-methyl bond eclipsing the adjacent axial carbon-hydrogen bond. Eclipsed bonds are also calculated for other inositol hexamethyl ether stereoisomers. Results contrast with the conformations of the equivalent hexaethylcyclohexane.

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