Effect of cyclosporine A and oligomycin on non‐specific permeability of the inner mitochondrial membrane
- 17 September 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 270 (1-2) , 108-110
- https://doi.org/10.1016/0014-5793(90)81245-j
Abstract
The effect of oligomycin and cyclosporine A on the induction of non-specific permeability of the inner mitochondrial membrane by Ca2+ was under study. Both oligomycin and cyclosporine A were able to prevent the activation of non-specific permeability, but cyclosporine A was the only agent which could restore initial permeability of the inner mitochondrial membrane. The effect of cyclosporine A was shown not to be mediated through redistribution of Ca2+ between different mitochondrial subpopulationsKeywords
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