Protein and Vitamin B

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Abstract
On a synthetic diet containing 20% of edestin and 5 gm. yeast extract per 100 gm. dry solids, many young rats die, showing typical kidney abnormality; elder rats are not adversely affected by the diet. These symptoms can be prevented by the addition of more yeast extract to the diet. The "protective" factor in yeast extract is not destroyed by autoclaving at 120[degree] for 4 1/2-5 hrs. There is a definite relation between protein and vitamin B and different proteins may require varying amounts of vitamin B that they may be properly metabolized. Edestin requires more yeast extract than either casein or egg-albumin for normal metabolism in young growing rats.