Abstract
Although neuroblastoma and glioma clonal cell lines are highly valuable in defining molecular events during differentiation, only recently has their usefulness been applied by the neurologist to explore such diverse mechanisms of disease as the Guillain-Barre syndrome, chronic motor polyneuropathy, morphine addiction and the chemotherapy of primary neoplasms of the nervous system. This editorial pointed out briefly the properties of these cell lines and illustrated their great potential in the investigation of neurologic disorders.