CONGENITAL INSULINOMA (NESIDIOBLASTOMA)

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 100  (7) , 352-356
Abstract
An insulinoma removed from a neonate with proved hyperinsulinemia was examined with the EM. The tumor was composed of pancreatic ductal epithelium and .beta. cells in direct contact and in lobular units. The pattern of the tumor, the morphologic evidence of .beta. cell-type activity in ductal cells, and the similarity of the arrangement of tumor cells to that observed in islet regeneration after subtotal pancreatectomy in the rat indicated that this tumor originated from ductal epithelium.

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