Genetic Modification of Electric Properties in an Excitable Membrane
Open Access
- 1 January 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (1) , 93-97
- https://doi.org/10.1073/pnas.69.1.93
Abstract
A behavioral deficiency produced by a single gene mutation in Paramecium aurelia was traced to impaired electric excitability of the cell membrane. Evidence is presented that the mutant membrane does not exhibit the normal depolarization-activated increase in calcium conductance responsible for regenerative depolarization in the wild type. Other electric properties characteristic of the wild-type membrane remain normal in the mutant.Keywords
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