There has long been a feeling among dermatologists that there is a definite relationship between carbohydrate metabolism and certain dermatoses. Particularly has it been believed that such a relation exists in acne vulgaris, in eczema and in furunculosis. To study this point various investigations have been made from time to time and the results published, but these reports have suffered from one rather common fault—conclusions have been drawn from an insufficient number of cases. In 1928 1 first reported the results of my study of the blood sugar level in a series of patients with common cutaneous disorders.1This series was made up of 205 different patients, and the conclusion was drawn that "it is safe to assume from the observations in acne vulgaris, seborrhea, furunculosis and psoriasis that hyperglycemia is not of great significance as an etiologic factor." Since I believed that that series of cases in which