Cell cycle parameters in radiation sensitive strains of Saccharomyces cerevisiae

Abstract
Summary Cell cycle parameters in different radiation-sensitive strains of diploid yeast were determined by flow cytofluorometry. The cell generation time was increased in homozygous rad2 and rad51 mutants but was not significanty different from the wild type in rad9 and rad6 mutants. All mutants had a longer G1-phase than the wild type. A lengthened S-phase was found in rad2 cells. Rad51 mutants displayed a considerably longer duration of G2.