Cancer: The Emerging Molecular Biology
- 15 January 2000
- journal article
- review article
- Published by Taylor & Francis in Hospital Practice
- Vol. 35 (1) , 63-74
- https://doi.org/10.3810/hp.2000.01.179
Abstract
Discoveries at the molecular level have greatly increased our understanding of how a normal cell becomes a tumor cell, responsive only to growth signals. Cancer emerges as fundamentally genetic, representing mutations in protooncogenes and tumor suppressor genes arising from multiple "hits" over long spans of time. The knowledge portends abilities to interrupt the process at a precancerous stage.Keywords
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