Studies of the molecular mechanisms in the regulation of telomerase activity
- 1 December 1999
- journal article
- review article
- Published by Wiley in The FASEB Journal
- Vol. 13 (15) , 2091-2104
- https://doi.org/10.1096/fasebj.13.15.2091
Abstract
Telomerase, a specialized RNA-directed DNA polymerase that extends telomeres of eukaryotic chromosomes, is repressed in normal human somatic cells but is activated during development and upon neopl...Keywords
Funding Information
- National Health and Medical Research Council
This publication has 166 references indexed in Scilit:
- Molecular interactions between telomerase and the tumor suppressor protein p53 in vitroOncogene, 1999
- Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone MouseCell, 1999
- Telomerase and cellular lifespan: Ending the debate?Nature Biotechnology, 1998
- Telomerase Activity in Human Leukemic Cell Lines Is Inhibited by Antisense Pentadecadeoxynucleotides Targeted against c-myc mRNABiochemical and Biophysical Research Communications, 1997
- Inhibition of Telomerase Activity by PKC Inhibitors in Human Nasopharyngeal Cancer Cells in CultureBiochemical and Biophysical Research Communications, 1997
- Induction of telomerase activity by UV-irradiation in Chinese hamster cellsOncogene, 1997
- Telomere structure and telomerase expression during mouse development and tumorigenesisEuropean Journal Of Cancer, 1997
- A survey of telomerase activity in human cancerPublished by Elsevier ,1997
- The genetic basis of human keratinocyte immortalisation in squatnous cell carcinoma development: The role of telomerase reactivationEuropean Journal Of Cancer, 1997
- Telomeres shorten during ageing of human fibroblastsNature, 1990